Research articles


2021

Immacolata Giordano, Lucia Pirone, Veronica Muratore, Eukene Landaluze, Coralia Pérez, Valerie Lang, Elisa Garde-Lapido, Monika Gonzalez-Lopez, Orhi Barroso-Gomila, Alfred C O Vertegaal, Ana M Aransay, Jose Antonio Rodriguez, Manuel S Rodriguez, James D Sutherland, Rosa Barrio (2021). SALL1 modulates CBX4 stability, nuclear bodies, and regulation of target genes. Frontiers in Cell and Developmental Biology, 9:715868.

DOI: 10.3389/fcell.2021.715868.

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland (2021). Identification of proximal SUMO-dependent interactors using SUMO-ID. Nature Communications 12, Article number: 6671.
 
DOI: 10.1038/s41467-021-26807-6.

2020

Robbert Q KimMohit MisraAlexis GonzalezInes TomaškovićDonghyuk ShinHermann SchindelinDmitri V FilippovHuib OvaaIvan ĐikićGerbrand J van der Heden van Noort (2020). Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chem. Eur. J. 2021, 27, 2506 – 2512
 
DOI : 10.1002/chem.202004590

Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Aitor Bermejo-Arteagabeitia, Carolina Da Fonseca, Orhi Barroso-Gomila, Mikel Azkargorta, Ibon Iloro, Olatz Pampliega, Ricardo AndradeNatalia Martín-MartínTess C Branon, Alice Y Ting, Jose A Rodríguez, Arkaitz CarracedoFelix Elortza, James D Sutherland, Rosa Barrio (2020). LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome. eLife 9, e55957.

DOI : 10.7554/eLife.55957

Tom Cremer, Marlieke L.M. Jongsma, Fredrik Trulsson, Alfred C.O. Vertegaal, Jacques J.C. Neefjes, Ilana Berlin. The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathwayCell Reports 34, 108659, January 19, 2021

DOI : 10.1016/j.celrep.2020.108659

Ganesh R. Pathare*, Alexiane Decout*, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Melenec, Beat Fierz, Nicolas H. Thomä‡ & Andrea Ablasser‡. Structural mechanism of cGAS inhibition by the nucleosome. Nature (2020) (epub ahead of print).

DOI : 10.1038/s41586-020-2750-6

Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H. Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C. Müller, Johannes Zuber, Matthias Geyer, Nicolas H. Thomä, Stefan Kubicek‡ & Georg E. Winter‡. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol 16, 1199–1207 (2020).

DOI : 10.1038/s41589-020-0594-x

Rosa G. Lopez‐Reyes, Grégoire Quinet, Maria Gonzalez‐Santamarta, Clément Larrue, Jean‐Emmanuel Sarry, Manuel S. Rodriguez. Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia. FEBS Open Bio (2020).

DOI: 10.1002/2211-5463.12950.

Mikołaj Słabicki*, Zuzanna Kozicka*, Georg Petzold#, Yen-Der Li, Manisha Manojkumar, Richard D. Bunker, Katherine A. Donovan, Quinlan L. Sievers, Jonas Koeppel, Dakota Suchyta, Adam S. Sperling, Emma C. Fink, Jessica A. Gasser, Li R. Wang, Steven M. Corsello, Rob S. Sellar, Max Jan, Dennis Gillingham, Claudia Scholl, Stefan Fröhling, Todd R. Golub, Eric S. Fischer, Nicolas H. Thomä‡ & Benjamin L. Ebert‡. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature (2020).

DOI: 10.1038/s41586-020-2374-x

Alicia K. Michael#, Ralph S. Grand#, Luke Isbel#, Simone Cavadini, Zuzanna Kozicka, Georg Kempf G, Richard D. Bunker, Andreas D. Schenk, Alexandra Graff-Meyer, Ganesh R. Pathare, Joscha Weiss, Syota Matsumoto, Lukas Burger, Dirk Schübeler, Nicolas H. Thomä. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science 368, 1460-1465 (2020).

DOI: 10.1126/science.abb0074.