All our publications are available in a single repository !
2021
2020
Ricardo Andrade(2020). LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome. eLife 9, e55957.
DOI : 10.7554/eLife.55957
, , , , . Cell Reports 34, 108659, January 19, 2021
DOI : 10.1016/j.celrep.2020.108659
Zuzanna Kozicka, Georg Petzold, Nicolas H. Thomä. Taking the brakes off targeted protein degradation. Cell Chemical Biology 27, 16-18 (2020).
DOI :10.1016/j.chembiol.2019.12.010
Ganesh R. Pathare*, Alexiane Decout*, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Melenec, Beat Fierz, Nicolas H. Thomä‡ & Andrea Ablasser‡. Structural mechanism of cGAS inhibition by the nucleosome. Nature (2020) (epub ahead of print).
DOI : 10.1038/s41586-020-2750-6
Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H. Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C. Müller, Johannes Zuber, Matthias Geyer, Nicolas H. Thomä, Stefan Kubicek‡ & Georg E. Winter‡. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol 16, 1199–1207 (2020).
DOI : 10.1038/s41589-020-0594-x
Rosa G. Lopez‐Reyes, Grégoire Quinet, Maria Gonzalez‐Santamarta, Clément Larrue, Jean‐Emmanuel Sarry, Manuel S. Rodriguez. Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia. FEBS Open Bio (2020).
DOI: 10.1002/2211-5463.12950.
Mikołaj Słabicki*, Zuzanna Kozicka*, Georg Petzold#, Yen-Der Li, Manisha Manojkumar, Richard D. Bunker, Katherine A. Donovan, Quinlan L. Sievers, Jonas Koeppel, Dakota Suchyta, Adam S. Sperling, Emma C. Fink, Jessica A. Gasser, Li R. Wang, Steven M. Corsello, Rob S. Sellar, Max Jan, Dennis Gillingham, Claudia Scholl, Stefan Fröhling, Todd R. Golub, Eric S. Fischer, Nicolas H. Thomä‡ & Benjamin L. Ebert‡. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature (2020).
DOI: 10.1038/s41586-020-2374-x
Grégoire Quinet, Maria Gonzalez-Santamarta, Clara Louche, Manuel S. Rodriguez. Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy. Molecules 2020, 25, 2352.
DOI: 10.3390/molecules25102352.
Alicia K. Michael#, Ralph S. Grand#, Luke Isbel#, Simone Cavadini, Zuzanna Kozicka, Georg Kempf G, Richard D. Bunker, Andreas D. Schenk, Alexandra Graff-Meyer, Ganesh R. Pathare, Joscha Weiss, Syota Matsumoto, Lukas Burger, Dirk Schübeler, Nicolas H. Thomä. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science 368, 1460-1465 (2020).
DOI: 10.1126/science.abb0074.
Maria Gonzalez-Santamarta, Grégoire Quinet, Diana Reyes-Garau, Brigitte Sola, Gaël Roué, Manuel S. Rodriguez (2020). Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma. In: Barrio R., Sutherland J., Rodriguez M. (eds) Proteostasis and Disease. Advances in Experimental Medicine and Biology, vol 1233. Springer, Cham.
DOI: 10.1007/978-3-030-38266-7_6.
David A. Pérez Berrocal, Katharina F. Witting, Huib Ovaa and Monique P.C. Mulder (2020). Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code. Front. Chem. 7:931.
2019
Nathalie Eisenhardt, Dragana Ilic, Easa Nagamalleswari, Andrea Pichler (2019). Chapter Eight - Biochemical characterization of SUMO-conjugating enzymes by in vitro sumoylation assays. Methods in Enzymology, Academic Press, Volume 618, Pages 167-185. ISBN 9780128163597.
DOI: 10.1016/bs.mie.2018.12.025
James D. Sutherland, Orhi Barroso-Gomila and Rosa Barrio (2019). Biotin-based Approaches for the Study of Ubiquitin and Ubiquitin-like Protein Modifications. SUMOylation and Ubiquitination: Current and Emerging Concepts, Caister Academic Press, Pages 101-122. ISBN 978-1-912530-12-0.