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2022

Magdalena Gorka, Helge Magnus Magnussen, Yogesh Kulathu (2022). Chemical biology tools to study Deubiquitinases and Ubl proteases. Seminars in Cell & Developmental Biology. ISSN 1084-9521.

DOI : 10.1016/j.semcdb.2022.02.006.

Open access
Ines Tomaskovic, Alexis Gonzalez, Ivan Dikic (2022). Ubiquitin and Legionella: From bench to bedside. Seminars in Cell & Developmental Biology, ISSN 1084-9521.
 
DOI : 10.1016/j.semcdb.2022.02.008
Open access
Orhi Barroso-Gomila, Veronica Muratore, Laura Merino-Cacho, Jose Antonio Rodriguez, Rosa Barrio, James D. Sutherland (2022). Studying the ubiquitin code through biotin-based labelling methods. Seminars in Cell & Developmental Biology, ISSN 1084-9521.
 
DOI : 10.1016/j.semcdb.2022.02.009
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Grégoire Quinet, Wendy Xolalpa, Diana Reyes-Garau, Núria Profitós-Pelejà, Mikel Azkargorta, Laurie Ceccato, Maria Gonzalez-Santamarta, Maria Marsal, Jordi Andilla, Fabienne Aillet, Francesc Bosch, Felix Elortza, Pablo Loza-Alvarez, Brigitte Sola, Olivier Coux, Rune Matthiesen, Gaël Roué, and Manuel S. Rodriguez (2022). "Constitutive Activation of p62/Sequestosome-1-Mediated Proteaphagy Regulates Proteolysis and Impairs Cell Death in Bortezomib-Resistant Mantle Cell Lymphoma" Cancers 14, no. 4: 923.
 
DOI : 10.3390/cancers14040923
Open access

2021

Barbara Mojsa, Michael H. Tatham, Lindsay Davidson, Magda Liczmanska, Emma Branigan, Ronald T. Hay (2021). Identification of SUMO Targets Associated With the Pluripotent State in Human Stem Cells. Molecular & Cellular Proteomics, Volume 20, 2021, 100164, ISSN 1535-9476.

DOI : 10.1016/j.mcpro.2021.100164

Open access
Fredrik Trulsson, Alfred C. O. Vertegaal (2021). Site-specific proteomic strategies to identify ubiquitin and SUMO modifications: Challenges and opportunities. Seminars in Cell & Developmental Biology, ISSN 1084-9521. 

DOI : 10.1016/j.semcdb.2021.11.006

Open access
Orhi Barroso-Gomila, Veronica Muratore, Laura Merino-Cacho, Jose Antonio Rodriguez, Rosa Barrio, James D. Sutherland (2022). Studying the ubiquitin code through biotin-based labelling methods. Seminars in Cell & Developmental Biology, ISSN 1084-9521.
 
DOI : 10.1016/j.semcdb.2022.02.009
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Yara Huppelschoten, Gerbrand J. van der Heden van Noort (2021). State of the art in (semi-)synthesis of Ubiquitin- and Ubiquitin-like tools. Seminars in Cell & Developmental Biology, ISSN 1084-9521.

DOI : 10.1016/j.semcdb.2021.11.025

Open access
Emma V. Rusilowicz-Jones, Ailbhe J. Brazel, Francesca Frigenti, Sylvie Urbé, Michael J. Clague (2021). Membrane compartmentalisation of the ubiquitin system. Seminars in Cell & Developmental Biology, ISSN 1084-9521.

DOI : 10.1016/j.semcdb.2021.11.016

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Evrydiki Asimaki, Kirill Petriukov, Christian Renz, Cindy Meister, Helle D.Ulrich (2021). Fast friends – Ubiquitin-like modifiers as engineered fusion partners. Seminars in Cell & Developmental Biology, ISSN 1084-9521.

DOI : 10.1016/j.semcdb.2021.11.013

Open access

Immacolata Giordano, Lucia Pirone, Veronica Muratore, Eukene Landaluze, Coralia Pérez, Valerie Lang, Elisa Garde-Lapido, Monika Gonzalez-Lopez, Orhi Barroso-Gomila, Alfred C O Vertegaal, Ana M Aransay, Jose Antonio Rodriguez, Manuel S Rodriguez, James D Sutherland, Rosa Barrio (2021). SALL1 modulates CBX4 stability, nuclear bodies, and regulation of target genes. Frontiers in Cell and Developmental Biology, 9:715868.

DOI: 10.3389/fcell.2021.715868.

Open access

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland (2021). Identification of proximal SUMO-dependent interactors using SUMO-ID. Nature Communications 12, Article number: 6671.

DOI: 10.1038/s41467-021-26807-6.

Open access
Maria Gonzalez-Santamarta, Corentin Bouvier, Manuel S. Rodriguez and Wendy Xolalpa (2021). Ubiquitin-chains dynamics and its role regulating crucial cellular processes. Seminars in Cell & Developmental Biology, ISSN 1084-9521.
 
DOI : 10.1016/j.semcdb.2021.11.023
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Zuzanna Kozicka, Nicolas H. Thomä. Haven't got a glue: Protein surface variation for the design of molecular glue degraders. Cell Chemical Biology (2021).
 
DOI : 10.1016/j.chembiol.2021.04.009
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Esmeralda Parra-Peralbo, Veronica Muratore, Orhi Barroso-Gomila, Ana Talamillo, James D. Sutherland, Rosa Barrio. Role of SUMOylation in neurodegenerative diseases and inflammation. Oxidative Stress and Disease. Proteostasis, CRC Press, Taylor & Francis Group (2021).
 
DOI : 10.1201/9781003048138-08
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2020

Barbara Mojsa, Michael H. Tatham, Lindsay Davidson, Magda Liczmanska, Jane E. Wright, Nicola Wiechens, Marek Gierlinski, Tom Owen-Hughes and Ronald T. Hay. SUMO maintains the chromatin environment of human induced pluripotent stem cells. Preprint.
 
DOI : 10.1101/2020.12.22.423944
Open access
Robbert Q Kim, Mohit Misra, Alexis Gonzalez, Ines Tomašković, Donghyuk Shin, Hermann Schindelin, Dmitri V Filippov, Huib Ovaa, Ivan Đikić, Gerbrand J van der Heden van Noort (2020). Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chem. Eur. J. 2021, 27, 2506 – 2512
 
DOI : 10.1002/chem.202004590
Open access
Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Ana Rosa Cortazar, Coralia Perez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland (2020). Identification of proximal SUMO-dependent interacts using SUMO-ID. Preprint.
 
DOI : 10.1101/2020.12.28.424528
Open access
Ana Talamillo, Orhi Barroso-Gomila, Immacolata Giordano, Leiore Ajuria, Marco Grillo, Ugo Mayor, Rosa Barrio (2020). The role of SUMOylation during development. Biochemical Society Transactions 48, 463–478.
 
DOI : 10.1042/BST20190390
Open access

Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Aitor Bermejo-Arteagabeitia, Carolina Da Fonseca, Orhi Barroso-Gomila, Mikel Azkargorta, Ibon Iloro, Olatz Pampliega, Ricardo Andrade, Natalia Martín-Martín, Tess C Branon, Alice Y Ting, Jose A Rodríguez, Arkaitz Carracedo, Felix Elortza, James D Sutherland, Rosa Barrio (2020). LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome. eLife 9, e55957.

DOI : 10.7554/eLife.55957

Open access

Tom Cremer, Marlieke L.M. Jongsma, Fredrik Trulsson, Alfred C.O. Vertegaal, Jacques J.C. Neefjes, Ilana Berlin. The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway. Cell Reports 34, 108659, January 19, 2021

DOI : 10.1016/j.celrep.2020.108659

Open access

Zuzanna Kozicka, Georg Petzold, Nicolas H. Thomä. Taking the brakes off targeted protein degradation. Cell Chemical Biology 27, 16-18 (2020).

DOI :10.1016/j.chembiol.2019.12.010

Open access

Ganesh R. Pathare*, Alexiane Decout*, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Melenec, Beat Fierz, Nicolas H. Thomä‡ & Andrea Ablasser‡. Structural mechanism of cGAS inhibition by the nucleosome. Nature (2020) (epub ahead of print).

DOI : 10.1038/s41586-020-2750-6

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Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H. Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C. Müller, Johannes Zuber, Matthias Geyer, Nicolas H. Thomä, Stefan Kubicek‡ & Georg E. Winter‡. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol 16, 1199–1207 (2020).

DOI : 10.1038/s41589-020-0594-x

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Rosa G. Lopez‐Reyes, Grégoire Quinet, Maria Gonzalez‐Santamarta, Clément Larrue, Jean‐Emmanuel Sarry, Manuel S. Rodriguez. Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia. FEBS Open Bio (2020).

DOI: 10.1002/2211-5463.12950.

Open access

Mikołaj Słabicki*, Zuzanna Kozicka*, Georg Petzold#, Yen-Der Li, Manisha Manojkumar, Richard D. Bunker, Katherine A. Donovan, Quinlan L. Sievers, Jonas Koeppel, Dakota Suchyta, Adam S. Sperling, Emma C. Fink, Jessica A. Gasser, Li R. Wang, Steven M. Corsello, Rob S. Sellar, Max Jan, Dennis Gillingham, Claudia Scholl, Stefan Fröhling, Todd R. Golub, Eric S. Fischer, Nicolas H. Thomä‡ & Benjamin L. Ebert‡. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature (2020).

DOI: 10.1038/s41586-020-2374-x

Open access
Ana Talamillo, Leiore Ajuria, Marco Grillo, Orhi Barroso-Gomila, Ugo Mayor, Rosa Barrio. SUMOylation in the control of cholesterol homeostasis. Open Biology (2020) 10:200054.
 
DOI: 10.1098/rsob.200054.
Open access

Grégoire Quinet, Maria Gonzalez-Santamarta, Clara Louche, Manuel S. Rodriguez. Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy. Molecules 2020, 25, 2352.

DOI: 10.3390/molecules25102352.

Open access

Alicia K. Michael#, Ralph S. Grand#, Luke Isbel#, Simone Cavadini, Zuzanna Kozicka, Georg Kempf G, Richard D. Bunker, Andreas D. Schenk, Alexandra Graff-Meyer, Ganesh R. Pathare, Joscha Weiss, Syota Matsumoto, Lukas Burger, Dirk Schübeler, Nicolas H. Thomä. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science 368, 1460-1465 (2020).

DOI: 10.1126/science.abb0074.

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Maria Gonzalez-Santamarta, Grégoire Quinet, Diana Reyes-Garau, Brigitte Sola, Gaël Roué, Manuel S. Rodriguez (2020). Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma. In: Barrio R., Sutherland J., Rodriguez M. (eds) Proteostasis and Disease. Advances in Experimental Medicine and Biology, vol 1233. Springer, Cham.

DOI: 10.1007/978-3-030-38266-7_6.

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David A. Pérez Berrocal, Katharina F. Witting, Huib Ovaa and Monique P.C. Mulder (2020). Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code. Front. Chem. 7:931.

Open access

2019

Nathalie Eisenhardt, Dragana Ilic, Easa Nagamalleswari, Andrea Pichler (2019). Chapter Eight - Biochemical characterization of SUMO-conjugating enzymes by in vitro sumoylation assays.  Methods in Enzymology, Academic Press, Volume 618, Pages 167-185. ISBN 9780128163597.

DOI: 10.1016/bs.mie.2018.12.025

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James D. Sutherland, Orhi Barroso-Gomila and Rosa Barrio (2019). Biotin-based Approaches for the Study of Ubiquitin and Ubiquitin-like Protein Modifications. SUMOylation and Ubiquitination: Current and Emerging Concepts, Caister Academic Press, Pages 101-122. ISBN 978-1-912530-12-0.

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